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Time for primary review 13 days. 1 Introduction Vascular smooth muscle cell (VSMC) proliferation is an important component of vessel wall remodelling in response to injury, for example, after ...

Cardiovascular Research, Review, Jamie Y. Jeremy, Daniel Rowe, Alison M. Emsley, Andrew C. Newby

Date : 15/08/1999 Item size : 746881 bytes

Abstract The effects of in vivo gene transfer of endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) genes on severe atherosclerosis were investigated in rabbits. Plasma lipid levels ...

Cardiovascular Research, Original Article, Toshio Hayashi, Daigo Sumi, Packiasamy A.R Juliet, Hisako Matsui-Hirai, Yukako Asai-Tanaka, Hatsuyo Kano, Akiko Fukatsu, Taku Tsunekawa, Asaka Miyazaki, ...

Date : 01/02/2004 Item size : 295188 bytes

In this study, we investigated the effect of elevated glucose concentrations on intracellular calcium (Ca2+i) signal transduction in response to stimulants of EDRF/nitric oxide release in cultured ...

Cardiovascular Research, Original Article, Galen M Pieper, Lynn Dondlinger

Date : 01/04/1997 Item size : 217987 bytes

Abstract Objective: The aim of this study was to investigate the contribution of nitric oxide/prostanoid-independent pathways to endothelium-dependent vasorelaxation in human conduit ...

Cardiovascular Research, Original Article, C.A Hamilton, R Williams, V Pathi, G Berg, K McArthur, A.R McPhaden, J.L Reid, A.F Dominiczak

Date : 01/04/1999 Item size : 344220 bytes

Abstract Aging is considered to be the major risk factor for the development of atherosclerosis and, therefore, for coronary artery disease. Apart from its vasodilator property, NO exerts inhibitory ...

Cardiovascular Research, Review, Ralf P. Brandes, Ingrid Fleming, Rudi Busse

Date : 01/05/2005 Item size : 563903 bytes

Introduction Vascular homeostasis is physiologically guaranteed by the balance between endothelium-derived substances with vasodilating and antithrombogenic properties, mainly nitric oxide (NO), and ...

European Heart Journal, Hypertension, Agostino Virdis, Emiliano Duranti, Rocchina Colucci, Chiara Ippolito, Erika Tirotta, Gianni Lorenzini, Nunzia Bernardini, Corrado Blandizzi, Stefano Taddei

Date : 14/11/2015

The present study was designed to examine the role of endothelium/nitric oxide in glibenclamide-induced relaxation in rat isolated aortic rings. Conclusion: These results indicate that ...

Cardiovascular Research, Original Article, Wai-Kei Chan, Xiaoqiang Yao, Wing-Hung Ko, Yu Huang

Date : 01/04/2000

Methods Acetylcholine relaxation in untreated and 6-week fenofibrate-treated Wistar rats was analyzed in the absence and presence of the NO synthase (NOS) inhibitor NG-nitro-l-arginine methyl ester ...

Cardiovascular Research, Original Article, Javier Blanco-Rivero, Iván Márquez-Rodas, Fabiano E. Xavier, Rosa Aras-López, Irene Arroyo-Villa, Mercedes Ferrer, Gloria Balfagón

Date : 15/07/2007

Elevation of an endogenous inhibitor of nitric oxide synthesis in experimental congestive heart failure The present study was designed to determine circulating ADMA levels and endothelium-dependent, ...

Cardiovascular Research, Original Article, Qingping Feng, Xiangru Lu, Amanda J Fortin, Anders Pettersson, Thomas Hedner, Robert L Kline, J.Malcolm O Arnold

Date : 01/03/1998

Abstract Objective: In vitro incubation of low-density lipoprotein (LDL) is reported to attenuate endothelium dependent relaxation mediated by acetylcholine (ACh) while not affecting ...

Cardiovascular Research, Original Article, Tamara V Lewis, Anthony M Dart, Jaye P.F Chin-Dusting

Date : 01/06/1997