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Abstract The discovery of the vascular endothelial growth factor (VEGF) family members VEGF, VEGF-B, placental growth factor (PlGF), VEGF-C and VEGF-D and their receptors VEGFR-1, -2 and -3 has ...

Cardiovascular Research, Review, Tuomas Tammela, Berndt Enholm, Kari Alitalo, Karri Paavonen

Date : 15/02/2005 Item size : 723617 bytes

The cardiac endothelium in cardiovascular homeostasis In the pathophysiology of HF, a pivotal role has been attributed to generalized endothelial dysfunction, in particular in the cardiac, pulmonary, ...

European Heart Journal, Clinical update, Shir Lynn Lim, Carolyn S.P. Lam, Vincent F.M. Segers, Dirk L. Brutsaert, Gilles W. De Keulenaer

Date : 14/08/2015 Item size : 707313 bytes

Abstract Objective: The concept of therapeutic angiogenesis with vascular endothelial growth factor (VEGF) has been validated in peripheral arterial disease. Various doses of recombinant VEGF or AIA ...

Cardiovascular Research, Original Article, Bernard Malavaud, Ivan Tack, Frédéric Jonca, Françoise Praddaude, Françoise Moro, Jean-Louis Ader, Jean Plouët

Date : 01/11/1997 Item size : 247534 bytes

Atherosclerosis is epidemiologically linked and causally related to the presence of risk factors Despite their diversity, major risk factors for cardiovascular disease such as hypercholesterolaemia, ...

Cardiovascular Research, Editorial, Raffaele De Caterina, Rosalinda Madonna

Date : 01/03/2009 Item size : 231905 bytes

Pathophysiogical aspects of platelet biology have, until recently, focussed on their relatively passive and reactive roles in minimising blood loss after injury, in contributing to the final stages ...

Cardiovascular Research, Editorial, Andrew D Blann

Date : 01/08/2004 Item size : 168301 bytes

Abstract The central role of vascular endothelial growth factor (VEGF) in angiogenesis in health and disease makes it attractive both as a therapeutic target for anti-angiogenic drugs and as a ...

Cardiovascular Research, Review, Ian Zachary, Georgia Gliki

Date : 16/02/2001 Item size : 675767 bytes

Abstract Aims Members of the growth factor family of neurotrophins [NTs; e.g. brain-derived neurotrophic factor (BDNF), neurotrophin-3 (NT3)] and their high-affinity receptors (tropomyosin-related ...

Cardiovascular Research, Original Article, Lucas W. Meuchel, Michael A. Thompson, Steven D. Cassivi, Christina M. Pabelick, Y.S. Prakash

Date : 01/09/2011

Abstract Objective: We have previously shown that downregulation of endothelial nitric oxide synthase (eNOS) expression by tumour necrosis factor-α (TNFα) resulted entirely from the marked ...

Cardiovascular Research, Original Article, Patrick F.H Lai, Farida Mohamed, Juan-Carlos Monge, Duncan J Stewart

Date : 01/07/2003

B2-kinin receptor plays a key role in B1-, angiotensin converting enzyme inhibitor-, and vascular endothelial growth factor-stimulated in vitro angiogenesis in the hypoxic mouse heart Abstract Aims ...

Cardiovascular Research, Original Article, Lourdes Sanchez de Miguel, Shiva Neysari, Sonja Jakob, Marco Petrimpol, Nicole Butz, Andrea Banfi, Christian E. Zaugg, Rok Humar, Edouard J. Battegay

Date : 01/10/2008

Effects of nebivolol on proliferation and apoptosis of human coronary artery smooth muscle and endothelial cells The aim of this study was to investigate the effects of the new β-blocker ...

Cardiovascular Research, Original Article, B.R Brehm, S.C Wolf, D Bertsch, M Klaussner, S Wesselborg, S Schüler, K Schulze-Osthoff

Date : 01/02/2001