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The role of reactive oxygen species and redox signalling in cardiovascular disease Reactive oxygen species (ROS) are generated during regulated physiological processes, and play a critical function ...

European Heart Journal, Clinical update, Keyvan Karimi Galougahi, Charalambos Antoniades, Stephen J. Nicholls, Keith M. Channon, Gemma A. Figtree

Date : 01/07/2015 Item size : 398285 bytes

The cardiac endothelium in cardiovascular homeostasis In the pathophysiology of HF, a pivotal role has been attributed to generalized endothelial dysfunction, in particular in the cardiac, pulmonary, ...

European Heart Journal, Clinical update, Shir Lynn Lim, Carolyn S.P. Lam, Vincent F.M. Segers, Dirk L. Brutsaert, Gilles W. De Keulenaer

Date : 14/08/2015 Item size : 707313 bytes

[...]M-CSF prevented post-inflammatory fibrosis and left ventricular dysfunction in wild-type but not in Nos2 mice. Introduction Inflammatory dilated cardiomyopathy (iDCM) is an important cause of ...

Cardiovascular Research, Original Article, Przemyslaw Blyszczuk, Corrine Berthonneche, Silvia Behnke, Marcel Glönkler, Holger Moch, Thierry Pedrazzini, Thomas F. Lüscher, Urs Eriksson, Gabriela ...

Date : 01/02/2013 Item size : 304238 bytes

Abstract Aims Previously, we showed an enhanced excitatory (N-methyl d-aspartate receptor-NR1) and decreased inhibitory neuronal nitric oxide (NO) synthase (nNOS) influence within the paraventricular ...

Cardiovascular Research, Original Article, Neeru M. Sharma, Hong Zheng, Parmender P. Mehta, Yi-Fan Li, Kaushik P. Patel

Date : 01/11/2011 Item size : 307597 bytes

[...]endothelial mitochondria are centrally involved in maintaining the fine regulatory balance between mitochondrial calcium concentration, reactive oxygen species (ROS) production, and ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Sean Michael Davidson

Date : 01/10/2010 Item size : 527437 bytes

An expanding body of evidence indicates that certain dietary patterns can influence cardiovascular health and primary prevention of CVD by modifying risk factors such as obesity, dyslipidemia, and ...

Cardiovascular Research, Editorial, Claudio Napoli, William C. Stanley, Louis J. Ignarro

Date : 15/01/2007 Item size : 226859 bytes

Evidence for the existence of apoptosis in the human heart has been reported in various cardiac diseases, including ischemic and non-ischemic heart failure, myocardial infarction and ...

Cardiovascular Research, Review, Giora Z. Feuerstein, Peter R. Young

Date : 01/02/2000 Item size : 352446 bytes

Abstract Objectives: To examine the relative roles of eNOS and iNOS (endothelial and inducible nitric oxide synthases) on basal and β-adrenergic receptor (β-AR)-stimulated arterial hemodynamic ...

Cardiovascular Research, Original Article, Mohamed A. Gaballa, Thomas E. Raya, Craig A. Hoover, Steven Goldman

Date : 01/06/1999 Item size : 227370 bytes

Chronic cardiotoxicity, which ranges from an incidence of 1% at a cumulative dose of 550 mg/m2 to >30% at cumulative doses above 5601160 mg/m2, can occur at any time after initiation of treatment and ...

Cardiovascular Research, Editorial, Charles F. McTiernan

Date : 01/02/2011 Item size : 177302 bytes

Heart failure (HF) is the leading cause of morbidity and mortality in industrialized countries with direct and indirect costs in 2012 across the globe of $108 billion per annum,1 making this ...

European Heart Journal, Review, Thomas Münzel, Tommaso Gori, John F. Keaney, Christoph Maack, Andreas Daiber

Date : 07/10/2015 Item size : 606980 bytes