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Methods/results: In isolated, constant pressure (CP) perfused guinea pig hearts a step change of arterial pCO2 from 38.6 to 61.4 mm Hg induced a bi-phasic flow response with an early transient ...

Cardiovascular Research, Original Article, Anke Heintz, Thea Koch, Andreas Deussen

Date : 01/04/2005 Item size : 258820 bytes

Abstract Objective: Because statins promote endogenous nitric oxide (NO) production in vessels by increasing endothelial nitric oxide synthase (eNOS), we evaluated the clinical benefit and efficiency ...

Cardiovascular Research, Original Article, Jean-Noel Trochu, Seema Mital, Xiao-ping Zhang, Xiaobin Xu, Manuel Ochoa, James K Liao, Fabio A Recchia, Thomas H Hintze

Date : 01/11/2003 Item size : 293750 bytes

Isoproterenol‐induced heart failure in the rat is associated with nitric oxide‐dependent functional alterations of cardiac function Tel: +421 2 50117 376, Fax: +421 2 50117 100, Email: ...

European Journal of Heart Failure, Krenek, Peter, Kmecova, Jana, Kucerova, Dana, Bajuszova, Zuzana, Musil, Peter, Gazova, Andrea, Ochodnicky, Peter, Klimas, Jan, Kyselovic, Jan

Date : 01/02/2009 Item size : 178559 bytes

Concentric left ventricular remodeling in endothelial nitric oxide synthase knockout mice by chronic pressure overload Abstract Objective: Heart failure as a consequence of sustained hemodynamic ...

Cardiovascular Research, Original Article, Hartmut Ruetten, Stefanie Dimmeler, Doris Gehring, Christian Ihling, Andreas M. Zeiher

Date : 01/06/2005 Item size : 280237 bytes

Western blotting and band optical density used to compare tissue from stunned territory (S), non-stunned territory (IC) and sham control animals (SC) demonstrated this was associated with an increase ...

Cardiovascular Research, Original Article, Christopher S.R. Baker, Ornella Rimoldi, Paolo G. Camici, Edward Barnes, Matilde R. Chacon, Tanya Y. Huehns, Dorian O. Haskard, Julia M. Polak, Roger J.C. ...

Date : 15/08/1999

Elevation of an endogenous inhibitor of nitric oxide synthesis in experimental congestive heart failure The present study was designed to determine circulating ADMA levels and endothelium-dependent, ...

Cardiovascular Research, Original Article, Qingping Feng, Xiangru Lu, Amanda J Fortin, Anders Pettersson, Thomas Hedner, Robert L Kline, J.Malcolm O Arnold

Date : 01/03/1998

Abstract Objective: The role of nitric oxide (NO) in myocardial ischemia/reperfusion injury remains controversial as both NO donors and NO synthase (NOS) inhibitors have shown to be ...

Cardiovascular Research, Original Article, Friedrich Brunner, Robert Maier, Penelope Andrew, Gerald Wölkart, Rudolf Zechner, Bernd Mayer

Date : 01/01/2003

Abstract Aims Nitroglycerin (GTN) acts through release of a nitric oxide (NO)-related activator of soluble guanylate cyclase in vascular smooth muscle. Besides enzymatic GTN bioactivation catalysed ...

Cardiovascular Research, Original Article, Gerald Wölkart, M. Verena Wenzl, Matteo Beretta, Heike Stessel, Kurt Schmidt, Bernd Mayer

Date : 15/07/2008

Abstract Objective: Cardiac parasympathetic nerve activity is reduced in most cardiovascular disease states, and this may contribute to enhanced cardiac sympathetic responsiveness. Disruption of ...

Cardiovascular Research, Original Article, E.J.F. Danson, Y.H. Zhang, C.E. Sears, A.R. Edwards, B. Casadei, D.J. Paterson

Date : 01/09/2005

Protein expression, vascular reactivity and soluble guanylate cyclase activity in mice lacking the endothelial cell nitric oxide synthase: contributions of NOS isoforms to blood pressure and heart ...

Cardiovascular Research, Original Article, Georg Kojda, Jorn B. Laursen, Santhini Ramasamy, Jonathan D. Kent, Sabine Kurz, Jana Burchfield, Edward G. Shesely, David G. Harrison

Date : 01/04/1999