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Abstract Objective: We tested the hypothesis that occlusion of the superior mesenteric artery induces late preconditioning against myocardial infarction and examined the effects of pharmacological ...

Cardiovascular Research, Original Article, You-Ping Wang, Hui Xu, Kazuhiro Mizoguchi, Masahiro Oe, Hajime Maeta

Date : 01/02/2001 Item size : 266841 bytes

Abstract It is well recognized that insulin resistance found in patients with type 2 diabetes and obesity is a major risk factor for cardiovascular disease. Since its discovery in the 1920s, insulin ...

Cardiovascular Research, REVIEWS: FOCUS ON INORGANIC NITRITE AND NITRATE, Qiujun Yu, Feng Gao, Xin L. Ma

Date : 15/02/2011 Item size : 415186 bytes

Tilarginine acts as an NOS inhibitor and early studies have suggested a potential clinical benefit. The TRIUMPH (Tilarginine Acetate Injection in a Randomized International Study in Unstable MI ...

Heart, JournalScan, Alistair Lindsay

Date : 01/08/2007

The beneficial actions of COX-2 appear to be mediated by the synthesis of PGE2 and/or PGI2. Since inhibition of iNOS in preconditioned myocardium blocks COX-2 activity whereas inhibition of COX-2 ...

Cardiovascular Research, Review, Roberto Bolli, Ken Shinmura, Xian-Liang Tang, Eitaro Kodani, Yu-Ting Xuan, Yiru Guo, Buddhadeb Dawn

Date : 15/08/2002 Item size : 570075 bytes

Of note, visible age-related signs such as male pattern boldness, grey hair, facial wrinkles as well as the presence of arcus corneae alone or in combination with appearance factors such as earlobe ...

European Heart Journal, Review, Giovanni G. Camici, Gianluigi Savarese, Alexander Akhmedov, Thomas F. Lüscher

Date : 21/12/2015 Item size : 709930 bytes

[...]AT2 receptor stimulation inhibits growth and promotes apoptosis, an important mechanism during development and tissue remodeling. [...]ANG stimulates the release of nitric oxide (NO)/cGMP via ...

Cardiovascular Research, Review, Olaf Jöhren, Andreas Dendorfer, Peter Dominiak

Date : 01/06/2004 Item size : 423872 bytes

[...]endothelial mitochondria are centrally involved in maintaining the fine regulatory balance between mitochondrial calcium concentration, reactive oxygen species (ROS) production, and ...

Cardiovascular Research, REVIEWS: FOCUS ON MITOCHONDRIA IN CARDIAC DISEASE, Sean Michael Davidson

Date : 01/10/2010 Item size : 527437 bytes

Studying mechanisms underlying shedding of endothelial membrane proteins could help patients at risk for myocardial infarction For almost half of its victims, it is the first sign of coronary artery ...

Cardiovascular Research, Editorial, Andrew C. Newby

Date : 01/07/2005 Item size : 157975 bytes

Evidence for the existence of apoptosis in the human heart has been reported in various cardiac diseases, including ischemic and non-ischemic heart failure, myocardial infarction and ...

Cardiovascular Research, Review, Giora Z. Feuerstein, Peter R. Young

Date : 01/02/2000 Item size : 352446 bytes

Ischemia/reperfusion-induced apoptosis: connecting nitric oxide and cell cycle regulators [...]serum stimulation of neonatal, terminally-differentiated cardiomyocytes, similarly to what happens in ...

Cardiovascular Research, Editorial, Carla Pignatti, Claudio Stefanelli

Date : 01/08/2003 Item size : 210601 bytes