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The host responds by producing nitric oxide (NO) and reactive oxygen species (ROS), and by releasing enzymes in order to kill the invading pathogen and clear the infection. Historically, NO was ...

Cardiovascular Research, Integrative physiology and pathophysiology, Anje Cauwels, Benjamin Vandendriessche, Jennyfer Bultinck, Benedicte Descamps, Elke Rogge, Tom Van Nieuwenhuysen, Magdalena Sips, ...

Date : 01/10/2013 Item size : 268579 bytes

Recap on NOS distribution and function in cardiovascular tissues Nitric oxide (NO) is a key universal signalling molecule in the cardiovascular system, acting on both acute and more chronic ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON REDUCING MYOCARDIAL ISCHAEMIA/REPERFUSION INJURY, Boris Manoury, Virginie Montiel, Jean-Luc Balligand

Date : 01/05/2012 Item size : 553690 bytes

The causes of primary PAHT remain largely unknown, but new studies have identified a gene located on chromosome 2 coding for bone morphogenetic protein receptor I (BMPR2), which belongs to the ...

Cardiovascular Research, Editorial, Eric Dubuis

Date : 01/06/2007 Item size : 175808 bytes

Currently, virtually all of the most prominent scientific journals have electronic versions that may be accessed over the Internet, and while journals that are exclusively electronic still have a ...

Cardiovascular Research, Editorial, David Garcia-Dorado, Klaus-Dieter Schlüter, Elizabeth A. Martinson, Hans Michael Piper

Date : 01/01/2005 Item size : 233599 bytes

Heart failure (HF) is the leading cause of morbidity and mortality in industrialized countries with direct and indirect costs in 2012 across the globe of $108 billion per annum,1 making this ...

European Heart Journal, Review, Thomas Münzel, Tommaso Gori, John F. Keaney, Christoph Maack, Andreas Daiber

Date : 07/10/2015 Item size : 606980 bytes

Abstract Increased production of reactive oxygen species (ROS) has been implicated in the pathogenesis of cardiovascular diseases. Enzymatic systems such as the mitochondrial respiratory chain, ...

Cardiovascular Research, Review, Hua Cai

Date : 01/10/2005 Item size : 587026 bytes

[...]the role of mitochondria goes beyond their capacity to create molecular fuel, to include the generation of reactive oxygen species, the regulation of calcium, and activation of cell ...

Cardiovascular Research, REVIEWS: SPOTLIGHT ON SMOOTH MUSCLE CELLS AND VASCULAR DISEASES, Emma Yu, John Mercer, Martin Bennett

Date : 15/07/2012 Item size : 535453 bytes

In 2003, Zhao et al.11 first reported a 50% reduction of infarct size (relative to the area at risk) by PostC in an acute canine model of 60 min left anterior descending artery (LAD) occlusion ...


Date : 01/05/2012 Item size : 559926 bytes

In addition to their lipid-lowering effects, one central biological action of statins is their ability to ameliorate the impaired bioavailability of NO.1 Mechanistically, this occurs through ...

Cardiovascular Research, Editorial, Stephan H. Schirmer, Christian M. Werner, Ulrich Laufs, Michael Böhm

Date : 01/06/2012 Item size : 181712 bytes

Abstract Although the specific roles of nitric oxide (NO) in the heart in general and on cardiac mitochondria in particular remain controversial, it is now clear that both endogenous and exogenous ...

Cardiovascular Research, Review, Sean M. Davidson, Michael R. Duchen

Date : 01/07/2006 Item size : 551284 bytes