Search terms
Results 1 - 10 of 116 - ordered by :
Pages: 1 2 3 4 5 6 7 ... 12

Abstract Several pathologies of the cardiovascular system are associated with an augmented production of nitric oxide and/or superoxide-derived oxidants and/or alteration in the antioxidant ...

Cardiovascular Research, Review, Gonzalo Peluffo, Rafael Radi

Date : 15/07/2007 Item size : 511451 bytes

Abstract Excessive production and/or inadequate removal of reactive oxygen species, especially superoxide anion (O2 have been implicated in the pathogenesis of many cardiovascular diseases, including ...

Cardiovascular Research, Review, Tohru Fukai, Rodney J Folz, Ulf Landmesser, David G Harrison

Date : 01/08/2002 Item size : 408641 bytes

Abstract Objective: We have shown previously that there is a relative nitric oxide deficiency at the level of vascular endothelium in the stroke-prone spontaneously hypertensive rat (SHRSP), a model ...

Cardiovascular Research, Original Article, M.Yvonne Alexander, M.Julia Brosnan, Carlene A Hamilton, Paul Downie, Alison M Devlin, Fiona Dowell, William Martin, Howard M Prentice, Timothy ...

Date : 15/08/1999 Item size : 290659 bytes

[...]AT2 receptor stimulation inhibits growth and promotes apoptosis, an important mechanism during development and tissue remodeling. [...]ANG stimulates the release of nitric oxide (NO)/cGMP via ...

Cardiovascular Research, Review, Olaf Jöhren, Andreas Dendorfer, Peter Dominiak

Date : 01/06/2004 Item size : 423872 bytes

Numerous clinical trials focused on therapeutic angiogenesis for the treatment of tissue ischaemia have not been as successful as those of preclinical studies. [...]additional studies are needed to ...

Cardiovascular Research, Review, Shyamal C. Bir, Yan Xiong, Christopher G. Kevil, Jincai Luo

Date : 01/07/2012 Item size : 723063 bytes

Time for primary review 13 days. 1 Introduction Vascular smooth muscle cell (VSMC) proliferation is an important component of vessel wall remodelling in response to injury, for example, after ...

Cardiovascular Research, Review, Jamie Y. Jeremy, Daniel Rowe, Alison M. Emsley, Andrew C. Newby

Date : 15/08/1999 Item size : 746881 bytes

Abstract Aims Vascular calcification often occurs with advancing age, atherosclerosis, and metabolic disorders such as diabetes mellitus and end-stage renal disease. Vascular calcification is ...

Cardiovascular Research, Original Article, Yosuke Kanno, Takeshi Into, Charles J. Lowenstein, Kenji Matsushita

Date : 01/01/2008 Item size : 286326 bytes

Yet, while modulation of cGMP-PKG has entered clinical practice for treating pulmonary hypertension or erectile dysfunction, translation of promising studies in experimental HF to clinical success ...

Cardiovascular Research, Review, Peter P. Rainer, David A. Kass

Date : 15/07/2016 Item size : 575491 bytes

Pathophysiology of septic shock and multi-organ failure Ill-defined genetic and cellular factors enable infectious insults to trigger an exaggerated and poorly regulated systemic inflammatory ...

Cardiovascular Research, Review, James F. Buckley, Mervyn Singer, Lucie H. Clapp

Date : 01/11/2006 Item size : 494521 bytes

Abstract There is convincing evidence that the prevalence of erectile dysfunction is increased among men with ischaemic heart disease. KeywordsNitric oxideErectile dysfunctionDiabetes ...

Cardiovascular Research, Original Article, Mark E. Sullivan, Cecil S. Thompson, Michael R. Dashwood, Masood A. Khan, Jamie Y. Jeremy, Robert J. Morgan, Dimitri P. Mikhailidis

Date : 15/08/1999 Item size : 375578 bytes