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Review of haemodynamic data of 151 cases with isolated aortic valve disease revealed severe pulmonary hypertension (pulmonary arterial systolic pressure of 60 mmHg or more) in 17 (11%). The left ...

British Heart Journal, Research Article, B Basu, G Cherian, S Krishnaswami, I P Sukumar, S John

Date : 01/11/1978

The effects of prostaglandin E1 on pulmonary circulation and left ventricular performance have been studied in 20 patients with mitral valve disease and pulmonary hypertension. Infusion of ...

British Heart Journal, Research Article, J Szczeklik, J S Dubiel, M Mysik, Z Pyzik, R Krol, T Horzela

Date : 01/12/1978

Short term administration of epoprostenol (mean dose 5.5 ng/kg/min) increased the mean cardiac index from 1.8 to 2.2 1/min/m2, improved pulmonary artery oxygen saturation from 48% to 57%, and ...

British Heart Journal, Research Article, D K Jones, T W Higenbottam, J Wallwork

Date : 01/03/1987

After recovery only a slight increase in cardiac index was seen while pulmonary vascular resistance was unchanged. The third patient felt ill after the acute bolus dose, and the blood pressure ...

British Heart Journal, Research Article, J Buch, A Wennevold

Date : 01/10/1981

OBJECTIVE--To determine whether epoprostenol (prostacyclin, PGI2) or heart-lung transplantation (HLT), or both improves survival of patients with severe pulmonary hypertension. [...]the benefits of ...

British Heart Journal, Research Article, T W Higenbottam, D Spiegelhalter, J P Scott, V Fuster, A T Dinh-Xuan, N Caine, J Wallwork

Date : 01/10/1993

In both groups on average, heart rate, pulmonary artery mean pressure, aortic mean pressure, and cardiac index increased significantly, while systemic vascular resistance fell significantly during ...

British Heart Journal, Research Article, E L Holloway, R A Polumbo, D C Harrison

Date : 01/05/1975

To assess the effectiveness of atrial septostomy by percutaneous balloon dilatation in patients with congenital heart defects or primary pulmonary hypertension. Twenty three patients (15 boys, eight ...

Heart, Research Article, B. D. Thanopoulos, D. Georgakopoulos, G. S. Tsaousis, S. Simeunovic

Date : 01/12/1996

Clinical, radiological, electrocardiographic, haemodynamic, and cineangiographic features of left ventricular endomyocardial fibrosis are described in 8 patients seen during the 10-year period ...

British Heart Journal, Research Article, G Vijayaraghavan, G Cherian, S Krishnaswami, I P Sukumar

Date : 01/05/1977

Initial right heart catheterisation in the 15 women showed severe resting pulmonary hypertension (mean (SD)) with pulmonary artery pressure (PAP) 57 (9) mm Hg, cardiac index 2.1 (0.5) l/min/m2, and ...

British Heart Journal, Research Article, F Brenot, P Herve, P Petitpretz, F Parent, P Duroux, G Simonneau

Date : 01/12/1993

T W Higenbottama, A Y Buttb, A T Dinh-Xauna, M Takaoa, G Cremonaa, S Akaminea aSection of Respiratory Medicine, Department of Medicine and Pharmacology, School of Medicine, University of Sheffield, ...

Heart, Paper, T W Higenbottam, A Y Butt, A T Dinh-Xaun, M Takao, G Cremona, S Akamine

Date : 01/02/1998