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The authors identified increased production of oxygen-derived species (ROS) including superoxide anion and hydrogen peroxide (H2O2) in the lungs of adult but not newborn Alk1+/ mice. Dysfunction of ...

Cardiovascular Research, Editorial, Livius V. d'Uscio

Date : 01/12/2011 Item size : 177916 bytes

Methods: Small intrapulmonary arteries (IPA) from rats were mounted on a myograph and PGF2α (3 μM)-induced tension recorded before and 40 min after replacing normal bath solution (5% CO2, 24 mM ...

Cardiovascular Research, Research Article, Marie Vaňková, Vladimir A. Snetkov, Greg A. Knock, Philip I. Aaronson, Jeremy P.T. Ward

Date : 01/02/2005 Item size : 254113 bytes

In older subjects, pulmonary hypertension associated with the acute respiratory distress syndrome, congenital heart disease with left-to-right shunt, and primary pulmonary hypertension remain ...

Cardiovascular Research, Editorial, Rosemary D Higgins, Martin Keszler

Date : 01/07/2001 Item size : 138473 bytes

The causes of primary PAHT remain largely unknown, but new studies have identified a gene located on chromosome 2 coding for bone morphogenetic protein receptor I (BMPR2), which belongs to the ...

Cardiovascular Research, Editorial, Eric Dubuis

Date : 01/06/2007 Item size : 175808 bytes

Combined effect of aerosolized iloprost and oxygen on assessment of pulmonary vasoreactivity in children with pulmonary hypertension Özlem Elkýran1, Cemþit Karakurt2, Gülendam Koçak3 ...

Date : 12/01/2017 Item size : 42649 bytes

Of importance, a considerable amount of information had already accumulated almost at the same time and had arrived at the same conclusions in non-vascular cells such as macrophages (see [6] for ...

Cardiovascular Research, Editorial, Santiago Lamas, Charles J. Lowenstein, Thomas Michel

Date : 15/07/2007

[...]excessive increases in pulmonary vascular resistance lead to pathology, expressed as high-altitude pulmonary hypertension and oedema in adult humans, persistent pulmonary hypertension in newborn ...

Cardiovascular Research, Original Article, Emilio A. Herrera, Roberto V. Reyes, Dino A. Giussani, Raquel A. Riquelme, Emilia M. Sanhueza, Germán Ebensperger, Paola Casanello, Natalia Méndez, ...

Date : 01/01/2008

Abstract Objective: Appetite-suppressant drug fenfluramine is implicated in primary pulmonary hypertension (PPH) but the molecular pathways that mediate this effect are unknown. A mouse model ...

Cardiovascular Research, Original Article, Cédric Blanpain, Emmanuel Le Poul, Jasmine Parma, Christiane Knoop, Michel Detheux, Marc Parmentier, Gilbert Vassart, Marc J Abramowicz

Date : 01/12/2003

KeywordsNitric oxidePulmonary circulationAbbreviationsNO, Nitric oxideINO, Inhaled nitric oxideppm, Parts per million, cGMP, Guanosine 35cyclic monophosphateGC, Guanylate cyclaseMetHb, ...

Cardiovascular Research, Review, Christopher S Hayward, Raymond P Kelly, Peter S Macdonald

Date : 15/08/1999

In separate groups of animals, the effects of the nitric oxide synthase inhibitor Nω-nitro-l-arginine (l-NNA) in combination with BMS-182874 (10 mg) during repeated hypoxia were ...

Cardiovascular Research, Original Article, Peter Holm, Jan Liska, Anders Franco-Cereceda

Date : 01/03/1998