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Introduction Primary pulmonary hypertension (PH) is a rare, progressive, and lethal disease of pulmonary vasculature characterized by enhanced vasoconstriction and vascular remodelling of small ...

Cardiovascular Research, Integrative physiology and pathophysiology, Krystyna Teichert-Kuliszewska, James N. Tsoporis, Jean-Francois Desjardins, Jun Yin, Liming Wang, Wolfgang M. Kuebler, Thomas G. ...

Date : 01/01/2015 Item size : 261468 bytes

[...]the effect of the rise in cytosolic calcium is amplified by enhanced calcium sensitivity of the actin/myosin interaction, achieved by the hypoxia-induced increase in Rho-kinase activity. Ion ...

Cardiovascular Research, Review in Review Focus Series on Hypoxia and the Pulmonary Circulation, E. Kenneth Weir, Andrea Olschewski

Date : 01/09/2006 Item size : 510430 bytes

The nomenclature of pulmonary hypertension has been updated over the years, reflecting different categories of pulmonary hypertension that may require unique treatments.1,2 Although the aetiologies ...

Cardiovascular Research, REVIEWS: FOCUS ON INORGANIC NITRITE AND NITRATE, Brian S. Zuckerbraun, Patricia George, Mark T. Gladwin

Date : 15/02/2011 Item size : 505144 bytes

RV-pulmonary arterial coupling predicts outcome in patients referred for pulmonary hypertension The adequacy of RV systolic functional adaptation to increased afterload was estimated either by a ...

Heart, Pulmonary vascular disease, Rebecca R Vanderpool, Michael R Pinsky, Robert Naeije, Christopher Deible, Vijaya Kosaraju, Cheryl Bunner, Michael A Mathier, Joan Lacomis, Hunter C Champion, Marc ...

Date : 01/01/2015

Except for the presence of moderate pulmonary hypertension, resting haemodynamics in these seven children were similar to those of normal children of equal age, but during exercise the postoperative ...

British Heart Journal, Research Article, T J Kulik, J L Bass, B P Fuhrman, J H Moller, J E Lock

Date : 01/07/1983

[...]heart sound after pulmonary arterial banding operation. If this interval is less than 40 ms, repeat catheterization should be carried out as such patients may have persisting pulmonary ...

British Heart Journal, Research Article, G R Cumming

Date : 01/05/1976

Before repair both isoprenaline infusion and 100% inspired oxygen produced significant falls in pulmonary artery pressure and pulmonary vascular resistance. Pulmonary artery banding performed in ...

British Heart Journal, Research Article, K F Hossack, J C Tewksbury, L M Reid

Date : 01/07/1989

Short term administration of epoprostenol (mean dose 5.5 ng/kg/min) increased the mean cardiac index from 1.8 to 2.2 1/min/m2, improved pulmonary artery oxygen saturation from 48% to 57%, and ...

British Heart Journal, Research Article, D K Jones, T W Higenbottam, J Wallwork

Date : 01/03/1987

After recovery only a slight increase in cardiac index was seen while pulmonary vascular resistance was unchanged. The third patient felt ill after the acute bolus dose, and the blood pressure ...

British Heart Journal, Research Article, J Buch, A Wennevold

Date : 01/10/1981

Analysis of individual results showed that the size of the response was inversely related to the severity of the pulmonary vascular disease. A favourable response was likely if the pretreatment mean ...

British Heart Journal, Research Article, A Rozkovec, J R Stradling, G Shepherd, J MacDermot, C M Oakley, C T Dollery

Date : 01/06/1988