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Introduction Primary pulmonary hypertension (PH) is a rare, progressive, and lethal disease of pulmonary vasculature characterized by enhanced vasoconstriction and vascular remodelling of small ...

Cardiovascular Research, Integrative physiology and pathophysiology, Krystyna Teichert-Kuliszewska, James N. Tsoporis, Jean-Francois Desjardins, Jun Yin, Liming Wang, Wolfgang M. Kuebler, Thomas G. ...

Date : 01/01/2015 Item size : 261468 bytes

An infusion of prostacyclin (PGI2) in four patients with pulmonary hypertension resulted in a dose-related decrease in the systemic and pulmonary vascular resistance and an increase in cardiac output.

British Heart Journal, Research Article, D N Guadagni, H Ikram, A H Maslowski

Date : 01/04/1981

There is a small subgroup of infants with transposition of the great arteries who show pulmonary vascular disease in the neonatal period that can adversely affect the surgical ...

British Heart Journal, Research Article, A Kumar, G P Taylor, G G Sandor, M W Patterson

Date : 01/05/1993

The 5th World Symposium on Pulmonary Hypertension in Nice in 2013 classified PH according to these underlying aetiologies, creating five groups: (1) pulmonary arterial hypertension (PAH); (2) PH due ...

Heart, Education in Heart, Marlieke L A Haeck, Hubert W Vliegen

Date : 15/02/2015

Increased pulmonary vascular resistance, right ventricular dysfunction, and reversible pulmonary vasoconstriction in type 2 pulmonary hypertension: who has it and are we missing a potential ...

European Journal of Heart Failure, Dickstein, Kenneth

Date : 01/03/2015 Item size : 64194 bytes

Abstract In 1991, Frostell and colleagues reported that breathing low concentrations of nitric oxide (NO) decreased pulmonary artery pressure (PAP) in awake lambs with experimental pulmonary ...

Cardiovascular Research, Review, Kenneth D. Bloch, Fumito Ichinose, Jesse D. Roberts, Warren M. Zapol

Date : 15/07/2007 Item size : 435466 bytes

[...]animals and humans require oxygen to survive, and a shortage of oxygen, hypoxia, can evoke life-threatening conditions. [...]pulmonary arterial blood pressure ranges <20 mmHg in healthy ...

Cardiovascular Research, Editorial to Review Focus Series on Hypoxia and the Pulmonary Circulation, Norbert Weissmann, Friedrich Grimminger, Werner Seeger

Date : 01/09/2006 Item size : 136670 bytes

Introduction With a normal pulmonary vasculature, the left ventricle is able to sustain the entire circulation, even in the absence of a functional right ventricle (RV).1,2 However, when left ...

European Heart Journal, Heart failure/cardiomyopathy, Vojtech Melenovsky, Seok-Jae Hwang, Grace Lin, Margaret M. Redfield, Barry A. Borlaug

Date : 21/12/2014

Abstract Objective: To determine whether pulmonary hypertension developed in a coronary artery-ligated rabbit model of left ventricular dysfunction (LVD) and to examine the effects of i.v. ...

Cardiovascular Research, Original Article, Graeme A Deuchar, Martin N Hicks, Stuart M Cobbe, Cheryl C Docherty, Margaret R MacLean

Date : 01/05/1998

Introduction Hypoxic vasoconstriction is unique to the pulmonary circulation and redistributes pulmonary blood flow from areas of low oxygen partial pressure to areas of normal or relativity high ...

Cardiovascular Research, Original Article, Benjamin Keserü, Eduardo Barbosa-Sicard, Ralph T. Schermuly, Hiromasa Tanaka, Bruce D. Hammock, Norbert Weissmann, Beate Fisslthaler, Ingrid Fleming

Date : 01/01/2010