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Ehjcardiovascrec

Pulmonary hypertension (PH) is characterized by vasoconstriction and abnormal remodelling of pulmonary vessels, leading to a progressive increase in pulmonary artery pressure and vascular stiffness, ...

Cardiovascular Research, Stenmark, Kurt R, Graham, Brian B

Date : 01/07/2018 Item size : 153216 bytes
Ehjournal

Introduction Current recommendations for aortic valve replacement (AVR) in patients presenting with aortic stenosis (AS) rely solely on the presence of two criteria: (i) The demonstration of a severe ...

European Heart Journal, Généreux, Philippe, Pibarot, Philippe, Redfors, Björn, Mack, Michael J, Makkar, Raj R, Jaber, Wael A, Svensson, Lars G, Kapadia, Samir, Tuzcu, E Murat, Thourani, ...

Date : 01/12/2017 Item size : 420315 bytes
Ehjcardiovascrec

Abstract Aims The pathogenic mechanisms of pulmonary arterial hypertension (PAH) remain unclear, but involve dysfunctional endothelial cells (ECs), dysregulated immunity and inflammation in the ...

Cardiovascular Research, Liang, Olin D., So, Eui-Young, Egan, Pamela C., Goldberg, Laura R., Aliotta, Jason M., Wu, Keith Q., Dubielecka, Patrycja M., Ventetuolo, Corey E., Reginato, Anthony M., ...

Date : 01/11/2017 Item size : 430423 bytes
Ehjcardiovascrec

Methods and results Expression of RAGE and its activating ligands, S100/calgranulins and high mobility group box 1 (HMGB1), were increased in both human and mouse pulmonary arterial smooth muscle ...

Cardiovascular Research, Jia, Daile, He, Yuhu, Zhu, Qian, Liu, Huan, Zuo, Caojian, Chen, Guilin, Yu, Ying, Lu, Ankang

Date : 01/05/2017 Item size : 364815 bytes
Ehjcardiovascrec

Current vasodilative treatment strategies, including endothelin receptor antagonists, prostacyclin analogues, and modulators of the nitric oxide (NO)-cGMP pathway such as inhaled NO, ...

Cardiovascular Research, Merkus, Daphne, Schermuly, Ralph T.

Date : 01/03/2017
Ehjcardiovascrec

Current vasodilative treatment strategies, including endothelin receptor antagonists, prostacyclin analogues, and modulators of the nitric oxide (NO)-cGMP pathway such as inhaled NO, ...

Cardiovascular Research, Merkus, Daphne, Schermuly, Ralph T.

Date : 01/03/2017
Ehjcardiovascrec

The structural changes in the pulmonary vasculature encompass endothelial cell proliferation, muscularization of the distal pulmonary arterioles and extracellular matrix deposition around the ...

Cardiovascular Research, Merkus, Daphne, Schermuly, Ralph T.

Date : 01/03/2017 Item size : 114571 bytes
Ehjcardiovascrec

The structural changes in the pulmonary vasculature encompass endothelial cell proliferation, muscularization of the distal pulmonary arterioles and extracellular matrix deposition around the ...

Cardiovascular Research, Merkus, Daphne, Schermuly, Ralph T.

Date : 01/03/2017 Item size : 114086 bytes
Ehjcardiovascrec

Current vasodilative treatment strategies, including endothelin receptor antagonists, prostacyclin analogues, and modulators of the nitric oxide (NO)-cGMP pathway such as inhaled NO, ...

Cardiovascular Research, Merkus, Daphne, Schermuly, Ralph T.

Date : 01/03/2017 Item size : 138091 bytes
Ehjcardiovascrec

Pulmonary arterial hypertension (PAH) is a devastating disease of the pulmonary vasculature in which vasoconstriction, inflammation, and a cancer-like phenotype, defined as excessive cell ...

Cardiovascular Research, Wu, Danchen, Archer, Stephen L.

Date : 01/07/2016