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Based on these observations and the biological effects induced by ET-1, including profound vasoconstriction, pro-inflammatory actions, mitogenic and proliferative effects, stimulation of free radical ...

Cardiovascular Research, Review, Felix Böhm, John Pernow

Date : 01/10/2007 Item size : 470334 bytes

Dr Julian P J Halcox Vascular Physiology Unit, Institute of Child Health, 30 Guildford Street, London WC1N 1EH, UK; Atherosclerosis is a chronic vascular inflammatory disease, ...

Heart, Mini-symposium, J P J Halcox, J E Deanfield

Date : 01/10/2005

Abstract Endothelial production of nitric oxide (nitrogen monoxide, NO) has become a major research area in vascular biology. The aim of this review is to examine the cellular and molecular ...

Cardiovascular Research, Review, Michael T Gewaltig, Georg Kojda

Date : 01/08/2002 Item size : 486616 bytes

[...]reducing heart rate could protect the endothelium and slow the onset of atherosclerosis. Context Resting heart rate is a basic and simple physiological parameter of the physical examination ...

Cardiovascular Research, Review, Eric Thorin, Nathalie Thorin-Trescases

Date : 01/10/2009 Item size : 455435 bytes

While synthetic peroxisome proliferator-activated receptor PPARα (fibrates) and PPARγ (thiazolinediones) agonists are used clinically in the treatment of hyperlipidaemia and diabetes, ...

Cardiovascular Research, Editorial, Nathalie Thorin-Trescases, Eric Thorin

Date : 01/03/2010 Item size : 167831 bytes

Abstract Aim Mortality, predominantly due to cardiovascular events, is high in patients with chronic kidney disease (CKD) and left ventricular hypertrophy (LVH) is a strong risk factor. There was no ...

Eur Heart J Cardiovasc Imaging, ORIGINAL ARTICLES, Dimitrios Poulikakos, Louise Ross, Alejandro Recio-Mayoral, Della Cole, Jocelyn Andoh, Nihil Chitalia, Rajan Sharma, Juan Carlos Kaski, Debasish ...

Date : 01/01/2014

Responses to cumulative intra-arterial doses of the endothelium-dependent dilator bradykinin (BK; n=56; 20, 40, 80 pmol/min) and the nitric oxide donor glyceryl trinitrate (GTN; n=54; 4, 8, 16 ...

Cardiovascular Research, Original Article, Nivedita Singh, Jonathan Graves, Paul D Taylor, Raymond J MacAllister, Donald R.J Singer

Date : 01/10/2002

Abstract Objective: Although type 2 diabetes is recognized as an independent risk factor for cardiovascular disease and cardiovascular disease is associated with endothelial dysfunction, the ...

Cardiovascular Research, Original Article, Marcel A van de Ree, Menno V Huisman, Frits H de Man, Jan C van der Vijver, A.Edo Meinders, Gerard J Blauw

Date : 01/11/2001

[...]most of us now recognise that the beneficial effects of statins on the early cardiovascular events reduction in major clinical trials may involve mechanisms that modify endothelial function, ...

Cardiovascular Research, Letter to the Editor, Kaeng W. Lee, Dirk C. Felmeden, Gregory Y.H. Lip

Date : 01/04/2002

Atherosclerotic vascular disease does occur in the IMA and, as you correctly point out, may be observed in the setting of cardiac transplant arteriopathy. Cardiac surgical practice at each centre ...

Cardiovascular Research, Reply to Letter to the Editor, Subodh Verma, Lawrence Ko, Todd J Anderson

Date : 01/10/2001