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Introduction Efficiency of excitationcontraction in the adult ventricular myocyte is enhanced by the structural features of this highly organised cell, with its scalloped surface formed by periodic ...

Cardiovascular Research, Original Article, Julia Gorelik, Lin Q. Yang, Yanjun Zhang, Max Lab, Yuri Korchev, Sian E. Harding

Date : 01/12/2006 Item size : 223827 bytes

Methods and results We used several types of cultured mouse, rat, and bovine cells from the cardiovascular system, and evaluated mitochondrial morphology, reactive oxygen species (ROS) levels, and ...

Cardiovascular Research, Original Article, Tianzheng Yu, Shey-Shing Sheu, James L. Robotham, Yisang Yoon

Date : 15/07/2008 Item size : 328023 bytes

Methods: Rat mesenteric small arteries (RMSA) were mounted on a pressure myograph and the functional (lumen diameter and Ca2+ oscillations) and ultrastructural effects of the phosphatase inhibitor ...

Cardiovascular Research, Original Article in Review Focus Series on Caveolae in Cardiovascular Signaling, Linda Shaw, Michele A. Sweeney, Stephen C. O'Neill, Carolyn J.P. Jones, Clare Austin, Michael ...

Date : 01/03/2006 Item size : 281926 bytes

Abstract Objective: Contractions of isolated, single myocytes of guinea pig heart stimulated at 37°C consist of a phasic component and a voltage dependent tonic component. Conclusions: Tonic ...

Cardiovascular Research, Original Article, Krzysztof Emanuel, Urszula Mackiewicz, Bohdan Lewartowski

Date : 01/10/2001 Item size : 253435 bytes

Abstract Objective: Maintenance of the mitochondrial membrane potential (Δψm) is fundamental for the normal performance and survival of cells such as cardiomyocytes, that have a high energy ...

Cardiovascular Research, Original Article, Anthony Mathur, Ying Hong, Barbara K. Kemp, Alberto Alvarez Barrientos, Jorge D. Erusalimsky

Date : 01/04/2000 Item size : 262159 bytes

Methods: Lp(a) was isolated by affinity chromatography from plasma of apparently healthy fasting donors with serum Lp(a) concentrations 20 mg/dl. Platelet-rich plasma (PRP) or washed platelets were ...

Cardiovascular Research, Original Article, Loukas D Tsironis, John V Mitsios, Haralampos J Milionis, Moses Elisaf, Alexandros D Tselepis

Date : 01/07/2004 Item size : 272849 bytes

Abstract Objective The outward current flowing through the two-pore domain acid-sensitive potassium channel TASK-1 (ITASK) and its inhibition via α1-adrenergic receptors was studied in rat ...

Cardiovascular Research, Original Article, Caroline Putzke, Konstantin Wemhöner, Frank B. Sachse, Susanne Rinné, Günter Schlichthörl, Xian Tao Li, Lucas Jaé, Ines Eckhardt, Erhard ...

Date : 01/07/2007 Item size : 276217 bytes

The purpose of the present study was to determine whether gender influences the acute electrophysiological actions of genistein at the level of isolated cardiac myocytes and to elucidate the ...

Cardiovascular Research, Original Article, Reginald Liew, Mark A Stagg, Joachim Chan, Peter Collins, Kenneth T MacLeod

Date : 01/01/2004 Item size : 280335 bytes

Abstract Objective: Neural crest-derived cells were previously shown to participate in vessel wall formation of the great thoracic arteries, and their contribution was proposed to affect morphology ...

Cardiovascular Research, Original Article, Maarten Bergwerff, Marco C. DeRuiter, Susan Hall, Robert E. Poelmann, Adriana C. Gittenberger-de Groot

Date : 01/10/1999 Item size : 319152 bytes

Abstract Objectives: The Ca2+ sensitivity of contractile protein-generated tension production was measured in the smooth muscle of the rabbit ductus arteriosus and compared with two neighbouring ...

Cardiovascular Research, Original Article, Catherine A. Crichton, Gordon C.S. Smith, Godfrey L. Smith

Date : 01/01/1997 Item size : 241752 bytes