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Stearoyl-CoA desaturase-1 (SCD1), which catalyzes the biosynthesis of monounsaturated fatty acids, affects the lipid composition and fluidity of the cell membrane. [...]we examined the effect of ...

Cardiovascular Research, Original Article, Xiaomei Qin, Jianwei Tian, Peng Zhang, Yanbo Fan, Li Chen, Youfei Guan, Yi Fu, Yi Zhu, Shu Chien, Nanping Wang

Date : 01/06/2007 Item size : 298015 bytes

The aim of this study was to determine the molecular mechanism involved in the proatherogenic effect of LTB4, BLT1 and BLT2 in atherosclerosis. [...]we characterized the expression of 5-lipoxygenase ...

Cardiovascular Research, Original Article, Eva Sánchez-Galán, Almudena Gómez-Hernández, Cristina Vidal, José Luis Martín-Ventura, Luis Miguel Blanco-Colio, Begoña ...

Date : 01/01/2009 Item size : 287690 bytes

Abstract Aims Proteasome inhibitors are a novel class of anticancer agents that induce tumour cell death via endoplasmic reticulum (ER) stress. Since ER stress is involved in the development of ...

Cardiovascular Research, Original Article, Hai Ying Fu, Tetsuo Minamino, Osamu Tsukamoto, Tamaki Sawada, Mitsutoshi Asai, Hisakazu Kato, Yoshihiro Asano, Masashi Fujita, Seiji Takashima, Masatsugu ...

Date : 01/09/2008 Item size : 291190 bytes

Abstract Aims Vascular calcification often occurs with advancing age, atherosclerosis, and metabolic disorders such as diabetes mellitus and end-stage renal disease. Vascular calcification is ...

Cardiovascular Research, Original Article, Yosuke Kanno, Takeshi Into, Charles J. Lowenstein, Kenji Matsushita

Date : 01/01/2008 Item size : 286326 bytes

Abstract Objective: In menopause, aging and decreased estrogen levels are risk factors contributing to impaired vascular function. Previously, in a young ovariectomized rat model, we demonstrated an ...

Cardiovascular Research, Original Article, Stephen J Armstrong, Yi Xu, Sandra T Davidge

Date : 01/02/2004 Item size : 268892 bytes

Systemic crude E. coli LPS administration decreased mtDNA copy number and mtDNA gene transcription in rat heart caused by oxidant deletion of mtDNA. The fall in copy number was reflected in ...

Cardiovascular Research, Research Article, Hagir B. Suliman, Karen E. Welty-Wolf, MarthaSue Carraway, Lynn Tatro, Claude A. Piantadosi

Date : 01/11/2004 Item size : 316915 bytes

Abstract Aims Diabetes mellitus (DM) is associated with poor clinical outcomes in humans with peripheral arterial disease (PAD) and in pre-clinical models of PAD, but the effects of glycaemic control ...

Cardiovascular Research, Integrative physiology and pathophysiology, Ayotunde O. Dokun, Lingdan Chen, Swapnil S. Lanjewar, Robert John Lye, Brian H. Annex

Date : 01/03/2014 Item size : 277742 bytes

CB1 and CB2 cannabinoid receptors differentially regulate the production of reactive oxygen species by macrophages Through selective expression of CB1 or CB2 to thioglycollate-elicited peritoneal ...

Cardiovascular Research, Original Article, Ki Hoon Han, Sunny Lim, Jewon Ryu, Cheol-Whan Lee, Yuna Kim, Ju-Hee Kang, Soon-Suk Kang, Yeong Ki Ahn, Chan-Sik Park, Jae Joong Kim

Date : 01/12/2009 Item size : 280901 bytes

Reactive oxygen species mediate cyclooxygenase-2 induction during monocyte to macrophage differentiation: critical role of NADPH oxidase Abstract Objective: The objective of this study was to ...

Cardiovascular Research, Original Article, Silvia Stella Barbieri, Sonia Eligini, Marta Brambilla, Elena Tremoli, Susanna Colli

Date : 15/10/2003 Item size : 302968 bytes

Abstract Aims Several experimental studies have demonstrated protection against cardiac ischaemiareperfusion injury achieved by pre-treatment with exogenous sphingosine-1-phosphate ...

Cardiovascular Research, Original Article, Ulrich Hofmann, Natalie Burkard, Carolin Vogt, Annemarie Thoma, Stefan Frantz, Georg Ertl, Oliver Ritter, Andreas Bonz

Date : 15/07/2009 Item size : 284100 bytes