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Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells In this study, we tested (a) whether reactive oxygen species (ROS) and c-Src ...

Cardiovascular Research, Sato, Hiroko, Sato, Mahito, Kanai, Hiroyoshi, Uchiyama, Tsuyoshi, Iso, Tatsuya, Ohyama, Yoshio, Sakamoto, Hironosuke, Tamura, Junichi, Nagai, Ryozo, Kurabayashi, Masahiko

Date : 01/09/2005

Abstract Objective: The primary aim of this study was to investigate whether activation of Na influx via voltage-gated Na channels can elevate sub-sarcolemmal (fuzzy-space [Na] and transiently ...

Cardiovascular Research, Silverman, Benjamin d.Z, Warley, Alice, Miller, Jonathan I.A, James, Andrew F, Shattock, Michael J

Date : 15/03/2003 Item size : 310990 bytes

Abstract Objective: Stimulation of A3 adenosine receptors has been shown to protect cardiac myocytes from ischemic injury, but the mechanism of this action is unknown. Hearts were then homogenized ...

Cardiovascular Research, Zucchi, Riccardo, Yu, Gongyuan, Ghelardoni, Sandra, Ronca, Francesca, Ronca-Testoni, Simonetta

Date : 01/04/2001 Item size : 298141 bytes

Abstract Objectives: This study aims at clarifying the role of cellular Ca2+ overload and spontaneous sarcoplasmic reticulum (SR) Ca2+ release in the generation of early afterdepolarizations (EAD) by ...

Cardiovascular Research, Volders, Paul G.A, Kulcsár, Attila, Vos, Marc A, Sipido, Karin R, Wellens, Hein J.J, Lazzara, Ralph, Szabo, Bela

Date : 01/05/1997 Item size : 265973 bytes

The increased Zn2+ was prevented by 5-hydroxydecanoate (5HD) but was mimicked by diazoxide, implying that mitochondrial KATP channel opening may account for this effect. Since chelation of Zn2+ ...

Cardiovascular Research, Jang, Youngho, Wang, Huihua, Xi, Jinkun, Mueller, Robert A., Norfleet, Edward A., Xu, Zhelong

Date : 15/07/2007

At 6 weeks of diabetes, glucose tolerance, cardiac function, pancreatic insulin content and basal and post-heparin plasma lipolytic activity were determined. Time for primary review 26 days. 1 ...

Cardiovascular Research, Rodrigues, Brian, Cam, Margaret C, Kong, Jian, Goyal, Ramesh K, McNeill, John H

Date : 01/04/1997

Abstract Vascular responses to endothelium-dependent vasodilators are greatly impaired in vivo, while isolated blood vessels from animals with diabetes mellitus demonstrate less consistent degrees of ...

Cardiovascular Research, Oltman, Christine L, Gutterman, David D, C. Scott, Eric, Bocker, Jennifer M, Dellsperger, Kevin C

Date : 01/04/1997 Item size : 176315 bytes

Methods and results We analyzed the molecular signature and functional response of lung tissue and distal pulmonary arteries (PAs) from individuals with (n23) and without (n16) PH. [...]a CD47 ...

Cardiovascular Research, Rogers, Natasha M., Sharifi-Sanjani, Maryam, Yao, Mingyi, Ghimire, Kedar, Bienes-Martinez, Raquel, Mutchler, Stephanie M., Knupp, Heather E., Baust, Jeffrey, Novelli, Enrico ...

Date : 01/01/2017 Item size : 560941 bytes