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Quantitation of protein kinase A-mediated trafficking of cardiac sodium channels in living cells Abstract Objective: Na+ current derived from expression of the principal cardiac Na+ channel, Nav1.5, ...

Cardiovascular Research, Original Article, Haifa Hallaq, Zhenjiang Yang, Prakash C. Viswanathan, Koji Fukuda, Wangzhen Shen, Dao W. Wang, K. Sam Wells, Jingsong Zhou, Jianxun Yi, Katherine T. Murray

Date : 01/11/2006

Effects of thyroid status on expression of voltage-gated potassium channels in rat left ventricle Abstract Objective: Thyroid hormone modifies cardiac action potentials and outward potassium ...

Cardiovascular Research, Original Article, Atsushi Nishiyama, Fukushi Kambe, Kaichiro Kamiya, Hisao Seo, Junji Toyama

Date : 01/11/1998

Introduction Endothelial dysfunction in response to various stimuli initiates the development of atherosclerosis, and reactive oxygen species (ROS) accelerate atherosclerotic lesion formation and ...

Cardiovascular Research, Original Article, Hiroshi Ohkawara, Toshiyuki Ishibashi, Shu-ichi Saitoh, Nobutaka Inoue, Koichi Sugimoto, Masashi Kamioka, Hironori Uekita, Takashi Kaneshiro, Katsuya Ando, ...

Date : 01/12/2010

Methods: Standard whole-cell patch clamp techniques were used to study the effects of multiple concentrations of each drug. The magnitude of voltage-dependent block was directly related to the ...

Cardiovascular Research, Original Article, Lixia Yue, Jian Lin Feng, Zhiguo Wang, Stanley Nattel

Date : 01/04/2000

Abstract Objective: In various cell types, membrane-associated guanylate kinases proteins called MAGUK play a major role in the spatial localization and clustering of ion channels. Here, we studied ...

Cardiovascular Research, Original Article, David Godreau, Roger Vranckx, Ange Maguy, Catherine Rücker-Martin, Catherine Goyenvalle, Salah Abdelshafy, Sophie Tessier, Jean-Paul Couétil, ...

Date : 01/12/2002

Abstract Objective Previous studies from our laboratory and others found that NO is a potent inducer of heme oxygenase-1 (HO-1) gene transcription in vascular smooth muscle cells (SMC), however, the ...

Cardiovascular Research, Original Article, Xiao-ming Liu, Kelly J. Peyton, Diana Ensenat, Hong Wang, Mark Hannink, Jawed Alam, William Durante

Date : 15/07/2007

Conclusion: Increased nNOS activity and the resultant increased NO production in the septic mouse cremaster muscle are the key factors responsible for the deficit in conducted vasoconstriction along ...

Cardiovascular Research, Original Article, Rebecca L. McKinnon, Darcy Lidington, Michael Bolon, Yves Ouellette, Gerald M. Kidder, Karel Tyml

Date : 01/01/2006

Abstract Objective: The effects of capsaicin on sensory neurons are mediated by its interaction with a specific membrane receptor and opening of a non-selective cation channel. In the rat heart, ...

Cardiovascular Research, Original Article, Harold D Schultz, Elena E Ustinova

Date : 01/05/1998

Abstract Objective Sphingosine-1-phosphate (S-1-P), a potent lysophospholipid mediator which is released from platelets during clotting, activates a G-protein-gated inwardly rectifying K+ current ...

Cardiovascular Research, Original Article, Rikuo Ochi, Yasunori Momose, Kosuke Oyama, Wayne R. Giles

Date : 01/04/2006

Abstract Objective: This study was designed to investigate the cardioprotective effect of the novel lipophilic iron chelator salicylaldehyde isonicotinoyl hydrazone (SIH) against the oxidative stress ...

Cardiovascular Research, Original Article, Magda Horackova, Prem Ponka, Zenobia Byczko

Date : 18/08/2000