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Abstract The effects of in vivo gene transfer of endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) genes on severe atherosclerosis were investigated in rabbits. Plasma lipid levels ...

Cardiovascular Research, Original Article, Toshio Hayashi, Daigo Sumi, Packiasamy A.R Juliet, Hisako Matsui-Hirai, Yukako Asai-Tanaka, Hatsuyo Kano, Akiko Fukatsu, Taku Tsunekawa, Asaka Miyazaki, ...

Date : 01/02/2004 Item size : 295188 bytes

Abstract Objectives: The present study was undertaken to determine the effects of free ionized calcium influenced by either the anticoagulant used (citrate vs. heparin) or directly varying the ...

Cardiovascular Research, Original Article, Shaker A. Mousa, Jeffrey M. Bozarth, Mark S. Forsythe, Andrew Slee

Date : 01/09/2000 Item size : 261184 bytes

Abstract Vascular responses to endothelium-dependent vasodilators are greatly impaired in vivo, while isolated blood vessels from animals with diabetes mellitus demonstrate less consistent degrees of ...

Cardiovascular Research, Original Article, Christine L Oltman, David D Gutterman, Eric C. Scott, Jennifer M Bocker, Kevin C Dellsperger

Date : 01/04/1997 Item size : 177347 bytes

Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells Abstract Objectives: The objective was to study potential regulation of insulin-like growth ...

Cardiovascular Research, Original Article, Patrick Delafontaine, Li Ku

Date : 01/01/1997 Item size : 258249 bytes

The current study investigates the roles of RhoA, ROCK (rho kinase), PKC (protein kinase C), and CPI-17 (protein kinase C-potentiated phosphatase inhibitor of 17 kDa), molecules shown to play pivotal ...

Cardiovascular Research, Original Article, Zhongwen Xie, Wen Su, Zhenheng Guo, Huan Pang, Steven R. Post, Ming C. Gong

Date : 01/02/2006 Item size : 317839 bytes

Abstract Objective: The aim was to investigate the effects of adenosine on nitric oxide (NO) synthesis in vascular smooth muscle cells. The interleukin-1β-induced nitrite production by vascular ...

Cardiovascular Research, Original Article, Uichi Ikeda, Kenji Kurosaki, Ken-ichi Ohya, Kazuyuki Shimada

Date : 01/07/1997 Item size : 289157 bytes

Abstract Objective: Determine the effect of a matrix metalloproteinase inhibitor (MMPi) and angiotensin converting enzyme inhibitor (ACEi) on collagen, MMP, tissue inhibitors of MMPs (TIMPs) ...

Cardiovascular Research, Original Article, Hua Li, Heather Simon, Thomas M.A. Bocan, J.Thomas Peterson

Date : 01/05/2000 Item size : 289140 bytes

Abstract Objective: Butylated hydroxyanisole (BHA) is a synthetic phenolic compound that is a potent inducer of phase II genes. Since heme oxygenase-1 (HO-1) is a vasoprotective protein that is ...

Cardiovascular Research, Original Article, Xiao-ming Liu, Mohammed A. Azam, Kelly J. Peyton, Diana Ensenat, Amit N. Keswani, Hong Wang, William Durante

Date : 01/04/2007 Item size : 311185 bytes

Methods: We subjected 18 autonomically-blocked, chloralose-anesthetized, open-chest pigs to 1 h of pulmonary artery constriction to increase RV systolic pressure from 35±1 to 55±1 mmHg, ...

Cardiovascular Research, Original Article, Clifford Greyson, Ya Xu, Joshua Cohen, Gregory G. Schwartz

Date : 01/05/1997 Item size : 195011 bytes

[...]a higher PDT dose (100 J/cm2) was needed to significantly (P<0.001) inhibit the SMC mitogenic response associated with SMC injury. Conclusion: These results provide a mechanism to explain how, ...

Cardiovascular Research, Original Article, Randolph G Statius van Eps, Farzin Adili, Glenn M LaMuraglia

Date : 01/08/1997 Item size : 258272 bytes