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Abstract Objective: Interferon-γ (IFN-γ), a cytokine produced primarily by T cells and by activated macrophages, plays a central role in the pathogenesis of graft arterial disease ...

Cardiovascular Research, Original Article, Yutaka Furukawa, Sarah E Cole, Ravi V Shah, Yoshihiro Fukumoto, Peter Libby, Richard N Mitchell

Date : 01/08/2004

In this study, we examined the localization of the molecules involved in α1-adrenergic receptor signal relative to that of caveolin in the heart and the changes in caveolin expression during the ...

Cardiovascular Research, Original Article, Takayuki Fujita, Yoshiyuki Toya, Kousaku Iwatsubo, Takeshi Onda, Kazuo Kimura, Satoshi Umemura, Yoshihiro Ishikawa

Date : 01/09/2001

In addition to the ultrastructural alterations, Dispersyn and colleagues also demonstrated changes in the pattern of expression of the structural proteins titin, desmin, cardiotin, α-actinin, and ...

Cardiovascular Research, Editorial, G.Chad Hughes

Date : 01/08/2001

Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells In this study, we tested (a) whether reactive oxygen species (ROS) and c-Src ...

Cardiovascular Research, Original Article, Hiroko Sato, Mahito Sato, Hiroyoshi Kanai, Tsuyoshi Uchiyama, Tatsuya Iso, Yoshio Ohyama, Hironosuke Sakamoto, Junichi Tamura, Ryozo Nagai, Masahiko ...

Date : 01/09/2005

The goal of this study was to determine whether mitogen-activated protein (MAP) kinases, including extracellular signal-regulated kinase 1/2 (ERK1/2), c-Jun N-terminal kinase (JNK), and p38 MAP ...

Cardiovascular Research, Original Article, Narimasa Miho, Takafumi Ishida, Noriko Kuwaba, Mari Ishida, Keiko Shimote-Abe, Kumiko Tabuchi, Tetsuya Oshima, Masao Yoshizumi, Kazuaki Chayama

Date : 01/11/2005

Abstract Objective: The present studies were performed to examine the degradation of connexin43-containing gap junctions by the lysosome or the proteasome in normal and heat-stressed cultures of ...

Cardiovascular Research, Original Article, James G Laing, Peter N Tadros, Karen Green, Jeffrey E Saffitz, Eric C Beyer

Date : 01/06/1998

Mapping this region identified that the CCAAT-binding factor/nuclear factor-Y (CBF/NF-Y) binding to the CCAAT box was inhibited by DNR in HL-1 cardiac muscle cells and in perfused isolated mouse ...

Cardiovascular Research, Original Article, Ah-Mee Park, Hiroko Nagase, Lingling Liu, Shilpashree Vinod Kumar, Nava Szwergold, Chi-Ming Wong, Yuichiro J. Suzuki

Date : 01/04/2011

Introduction Atherosclerosis is a chronic inflammatory disease showing a major involvement of the immune system.1 In the atherosclerotic inflammatory milieu, T cells are recruited by adhesion ...

Cardiovascular Research, Vascular biology and angiogenesis, Kongyang Ma, Silin Lv, Bo Liu, Ziyi Liu, Yuhong Luo, Wei Kong, Qingbo Xu, Juan Feng, Xian Wang

Date : 01/02/2013

Abstract Objectives: HMG CoA reductase inhibitors reduce cellular availability of mevalonate, a precursor in cholesterol synthesis. Since the cholesterol content of cell membranes is an important ...

Cardiovascular Research, Original Article, David F Gray, Henning Bundgaard, Peter S Hansen, Kerrie A Buhagiar, Anastasia S Mihailidou, Wendy Jessup, Keld Kjeldsen, Helge H Rasmussen

Date : 01/08/2000

Abstract Objective: The purpose of this study was to clarify the role of glycoxidation and lipid peroxidation of low-density lipoprotein (LDL) in ...

Cardiovascular Research, Original Article, Noriyuki Sakata, Noriko Uesugi, Shigeo Takebayashi, Ryoji Nagai, Tadashi Jono, Seikoh Horiuchi, Motohiro Takeya, Hiroyuki Itabe, Tatsuya Takano, Theingi ...

Date : 01/02/2001