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Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells Abstract Objectives: The objective was to study potential regulation of insulin-like growth ...

Cardiovascular Research, Original Article, Patrick Delafontaine, Li Ku

Date : 01/01/1997 Item size : 258249 bytes

The current study investigates the roles of RhoA, ROCK (rho kinase), PKC (protein kinase C), and CPI-17 (protein kinase C-potentiated phosphatase inhibitor of 17 kDa), molecules shown to play pivotal ...

Cardiovascular Research, Original Article, Zhongwen Xie, Wen Su, Zhenheng Guo, Huan Pang, Steven R. Post, Ming C. Gong

Date : 01/02/2006 Item size : 317839 bytes

Abstract Objective: The aim was to investigate the effects of adenosine on nitric oxide (NO) synthesis in vascular smooth muscle cells. The interleukin-1β-induced nitrite production by vascular ...

Cardiovascular Research, Original Article, Uichi Ikeda, Kenji Kurosaki, Ken-ichi Ohya, Kazuyuki Shimada

Date : 01/07/1997 Item size : 289157 bytes

Abstract Objective: Butylated hydroxyanisole (BHA) is a synthetic phenolic compound that is a potent inducer of phase II genes. Since heme oxygenase-1 (HO-1) is a vasoprotective protein that is ...

Cardiovascular Research, Original Article, Xiao-ming Liu, Mohammed A. Azam, Kelly J. Peyton, Diana Ensenat, Amit N. Keswani, Hong Wang, William Durante

Date : 01/04/2007 Item size : 311185 bytes

[...]a higher PDT dose (100 J/cm2) was needed to significantly (P<0.001) inhibit the SMC mitogenic response associated with SMC injury. Conclusion: These results provide a mechanism to explain how, ...

Cardiovascular Research, Original Article, Randolph G Statius van Eps, Farzin Adili, Glenn M LaMuraglia

Date : 01/08/1997 Item size : 258272 bytes

Oxidized low density lipoprotein induces apoptosis via generation of reactive oxygen species in vascular smooth muscle cells Abstract Objective: Death of vascular smooth muscle cell (VSMC) induced ...

Cardiovascular Research, Original Article, Chien-Cheng Hsieh, Mao-Hsiung Yen, Chia-Hung Yen, Ying-Tung Lau

Date : 01/01/2001 Item size : 374782 bytes

The angiopoietin–tie2 system in coronary artery endothelium prevents oxidized low-density lipoprotein-induced apoptosis Abstract Objectives: A healthy, intact coronary artery endothelium is ...

Cardiovascular Research, Original Article, Injune Kim, Sang-Ok Moon, Chang-Yeop Han, Youngmi Kim Pak, Sung Ki Moon, Jong Jun Kim, Gou Young Koh

Date : 01/03/2001

Abstract Objective: Interferon-γ (IFN-γ), a cytokine produced primarily by T cells and by activated macrophages, plays a central role in the pathogenesis of graft arterial disease ...

Cardiovascular Research, Original Article, Yutaka Furukawa, Sarah E Cole, Ravi V Shah, Yoshihiro Fukumoto, Peter Libby, Richard N Mitchell

Date : 01/08/2004

In this study, we examined the localization of the molecules involved in α1-adrenergic receptor signal relative to that of caveolin in the heart and the changes in caveolin expression during the ...

Cardiovascular Research, Original Article, Takayuki Fujita, Yoshiyuki Toya, Kousaku Iwatsubo, Takeshi Onda, Kazuo Kimura, Satoshi Umemura, Yoshihiro Ishikawa

Date : 01/09/2001

Mitochondrial reactive oxygen species and c-Src play a critical role in hypoxic response in vascular smooth muscle cells In this study, we tested (a) whether reactive oxygen species (ROS) and c-Src ...

Cardiovascular Research, Original Article, Hiroko Sato, Mahito Sato, Hiroyoshi Kanai, Tsuyoshi Uchiyama, Tatsuya Iso, Yoshio Ohyama, Hironosuke Sakamoto, Junichi Tamura, Ryozo Nagai, Masahiko ...

Date : 01/09/2005