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Abstract Objectives: This study aims at clarifying the role of cellular Ca2+ overload and spontaneous sarcoplasmic reticulum (SR) Ca2+ release in the generation of early afterdepolarizations (EAD) by ...

Cardiovascular Research, Original Article, Paul G.A Volders, Attila Kulcsár, Marc A Vos, Karin R Sipido, Hein J.J Wellens, Ralph Lazzara, Bela Szabo

Date : 01/05/1997 Item size : 219807 bytes

Methods The investigation was carried out in accordance with the Guide for the Care and Use of Laboratory Animals published by the US National Institutes of Health (NIH publication number 85-23, ...

Cardiovascular Research, Original Article, Yayoi Taniguchi, Naohiko Takahashi, Akira Fukui, Yasuko Nagano-Torigoe, Luong Cong Thuc, Yasushi Teshima, Tetsuji Shinohara, Osamu Wakisaka, Tatsuhiko Ooie, ...

Date : 01/12/2011 Item size : 257351 bytes

Abstract Objectives: Increasing evidence suggests that left ventricular remodeling is associated with a shift from fatty acid to glucose metabolism for energy production. The aim of this study was ...

Cardiovascular Research, Original Article, Nathalie Rosenblatt-Velin, Christophe Montessuit, Irène Papageorgiou, Jérôme Terrand, René Lerch

Date : 01/12/2001 Item size : 286213 bytes

At 6 weeks of diabetes, glucose tolerance, cardiac function, pancreatic insulin content and basal and post-heparin plasma lipolytic activity were ...

Cardiovascular Research, Original Article, Brian Rodrigues, Margaret C Cam, Jian Kong, Ramesh K Goyal, John H McNeill

Date : 01/04/1997 Item size : 178616 bytes

Abstract The effects of in vivo gene transfer of endothelial nitric oxide synthase (eNOS) and inducible NOS (iNOS) genes on severe atherosclerosis were investigated in rabbits. Plasma lipid levels ...

Cardiovascular Research, Original Article, Toshio Hayashi, Daigo Sumi, Packiasamy A.R Juliet, Hisako Matsui-Hirai, Yukako Asai-Tanaka, Hatsuyo Kano, Akiko Fukatsu, Taku Tsunekawa, Asaka Miyazaki, ...

Date : 01/02/2004 Item size : 295188 bytes

Abstract Objectives: The present study was undertaken to determine the effects of free ionized calcium influenced by either the anticoagulant used (citrate vs. heparin) or directly varying the ...

Cardiovascular Research, Original Article, Shaker A. Mousa, Jeffrey M. Bozarth, Mark S. Forsythe, Andrew Slee

Date : 01/09/2000 Item size : 261184 bytes

Abstract Vascular responses to endothelium-dependent vasodilators are greatly impaired in vivo, while isolated blood vessels from animals with diabetes mellitus demonstrate less consistent degrees of ...

Cardiovascular Research, Original Article, Christine L Oltman, David D Gutterman, Eric C. Scott, Jennifer M Bocker, Kevin C Dellsperger

Date : 01/04/1997 Item size : 177347 bytes

Reactive oxygen species stimulate insulin-like growth factor I synthesis in vascular smooth muscle cells Abstract Objectives: The objective was to study potential regulation of insulin-like growth ...

Cardiovascular Research, Original Article, Patrick Delafontaine, Li Ku

Date : 01/01/1997 Item size : 258249 bytes

The current study investigates the roles of RhoA, ROCK (rho kinase), PKC (protein kinase C), and CPI-17 (protein kinase C-potentiated phosphatase inhibitor of 17 kDa), molecules shown to play pivotal ...

Cardiovascular Research, Original Article, Zhongwen Xie, Wen Su, Zhenheng Guo, Huan Pang, Steven R. Post, Ming C. Gong

Date : 01/02/2006 Item size : 317839 bytes

Abstract Objective: The aim was to investigate the effects of adenosine on nitric oxide (NO) synthesis in vascular smooth muscle cells. The interleukin-1β-induced nitrite production by vascular ...

Cardiovascular Research, Original Article, Uichi Ikeda, Kenji Kurosaki, Ken-ichi Ohya, Kazuyuki Shimada

Date : 01/07/1997 Item size : 289157 bytes