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By reducing venous return and left ventricular end-diastolic pressure they lower myocardial oxygen demand and at the same time enhance blood flow to the sub-endocardium. Early small-scale studies ...

European Heart Journal, Thadani, U.

Date : 01/12/1996 Item size : 107935 bytes

The two largest randomized trials, the COURAGE and BARI-2D trials, both including patients with angiographically documented CAD, have failed to demonstrate a prognostic benefit of revascularization ...

European Heart Journal, Gaemperli, Oliver, Bengel, Frank M., Kaufmann, Philipp A.

Date : 01/09/2011 Item size : 493580 bytes

Abstract Aims Coronary endothelial dysfunction (ED), by predisposing to abnormal vasomotion, may cause chest pain in individuals with non-obstructed coronary arteries. Methods and results In 30 ...

European Heart Journal, Summers, Matthew R., Lerman, Amir, Lennon, Ryan J., Rihal, Charanjit S., Prasad, Abhiram

Date : 01/11/2011 Item size : 246861 bytes

β-adrenergic coronary dilation is of minor functional importance, α-adrenergic coronary constriction acts to attenuate increases in coronary blood flow during sympathetic activation under ...

European Heart Journal, Heusch, G.

Date : 01/12/1991 Item size : 99036 bytes

Available evidence also demonstrates lack of efficacy of thrombolysis in patients with AMI beyond 12h from symptom onset and a 12h time interval has been used in current guidelines as a cutoff time ...

European Heart Journal, Schömig, Albert, Ndrepepa, Gjin, Kastrati, Adnan

Date : 01/08/2006 Item size : 422925 bytes

[...]the diagnosis of coronary artery disease is conventionally applied only to patients who are shown to have significant narrowing of one or more major epicardial coronary artery. [...]it is the ...

European Heart Journal, Panza, Julio A.

Date : 01/04/2010

Controversies on acetylcholine-induced increases or decreases in coronary blood flow arise from obvious species differences, the role of endothelium in mediating vascular smooth muscle responses and ...

European Heart Journal, Heusch, G., Guth, B. D.

Date : 01/11/1989

Subendocardial perfusion measurements and quantification of the transmural perfusion gradient (TPG) could be more sensitive and specific for the detection of coronary artery disease (CAD). The ...

European Heart Journal, Danad, Ibrahim, Raijmakers, Pieter G., Harms, Hendrik J., Heymans, Martijn W., van Royen, Niels, Lubberink, Mark, Boellaard, Ronald, van Rossum, Albert C., Lammertsma, Adriaan ...

Date : 14/08/2014

The ischaemic cascade Coronary artery disease (CAD) is primarily a structural disease characterized by the build-up of atherosclerotic plaques in the coronary arteries. With progressive impingement ...

European Heart Journal, Gaemperli, Oliver, Lüscher, Thomas F., Bax, Jeroen J.

Date : 14/08/2013 Item size : 201427 bytes

Treadmill exercise at 6·5km h 1 with a 6% grade resulted in a mean heart rate of 209 ± 4 beats min 1 , with mean myocardial blood flow in the normally perfused left ventricular region of ...

European Heart Journal, Bache, R. J., Laxson, D. D.

Date : 01/01/1990 Item size : 109845 bytes