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Introduction Atrial fibrillation (AF) is an independent risk factor for thromboembolism and stroke, leading to an approximate three- to five-fold excess risk, and the prevention of thromboembolism is ...

Cardiovascular Research, Khan, Ahsan A, Lip, Gregory Y H

Date : 01/01/2019 Item size : 954052 bytes

Introduction Dyslipidaemia and inflammation are closely interconnected key drivers of atherosclerosis.1 Dysregulated lipid metabolism induces an inflammatory and immune response in atherosclerosis, ...

Cardiovascular Research, Tuñón, José, Badimón, Lina, Bochaton-Piallat, Marie-Luce, Cariou, Bertrand, Daemen, Mat J, Egido, Jesus, Evans, Paul C, Hoefer, Imo E, Ketelhuth, Daniel F J, ...

Date : 01/01/2019 Item size : 618947 bytes

Watch the Cardiovascular Research Onlife interview about The Big Beat Challenge withProfessor Jeremy Pearson, Associate Medical Director of the British Heart Foundation: ...

Cardiovascular Research, Samani, Nilesh J

Date : 01/01/2019 Item size : 107590 bytes

The aim of this study was to investigate if IL6 trans-signalling, estimated by a ratio between the binary and ternary complexes, associates with the risk of future cardiovascular events (CVE) in a ...

Cardiovascular Research, Ziegler, Louise, Gajulapuri, Ashwini, Frumento, Paolo, Bonomi, Alice, Wallén, Håkan, de Faire, Ulf, Rose-John, Stefan, Gigante, Bruna

Date : 01/01/2019 Item size : 336192 bytes

[...]chronic activation of Epac1 increases the propensity for ventricular arrhythmia by up-regulation of calmodulin protein. Cardiac Epac2, mostly studied in ventricular cardiomyocytes, is located ...

Cardiovascular Research, Pereira, Laetitia

Date : 01/01/2019 Item size : 152632 bytes

Alexander Lukasz, Philipp Kümpers, and their colleagues from the University Hospital Münster, Germany, have studied the mechanisms of breakdown of the endothelial glycocalyx.1 Using confocal ...

Cardiovascular Research, Morawietz, Henning

Date : 01/01/2019 Item size : 154294 bytes

The goal of revascularization in stable coronary artery disease (SCAD) is to relieve the myocardium from flow-limiting coronary artery disease. Positron emission tomography (PET) using tracers of ...

Cardiovascular Research, Berry, Colin, Bengel, Frank M

Date : 01/01/2019 Item size : 150596 bytes

Methods and results In a prospective, multicentre observational study, CFR was measured by 15O-water positron emission tomography as the ratio of stress to rest myocardial blood flow at baseline and ...

Cardiovascular Research, Aikawa, Tadao, Naya, Masanao, Obara, Masahiko, Manabe, Osamu, Magota, Keiichi, Koyanagawa, Kazuhiro, Asakawa, Naoya, Ito, Yoichi M, Shiga, Tohru, Katoh, Chietsugu, Anzai, ...

Date : 01/01/2019 Item size : 361857 bytes

Due to the famously limited amount of regenerative capacity of the myocardium, the only viable option for advanced HF patients is cardiac transplantation; however, donors hearts are in very short ...

Cardiovascular Research, Singh, Anand Prakash, Umbarkar, Prachi, Guo, Yuanjun, Force, Thomas, Gupte, Manisha, Lal, Hind

Date : 01/01/2019 Item size : 500135 bytes

More than 20years ago, pivotal studies reported that an increased C-reactive protein (CRP) level predicted poor outcome in patients with acute coronary syndrome, raising the hypothesis that systemic ...

Cardiovascular Research, Ferrante, Giuseppe, Condorelli, Gianluigi

Date : 01/01/2019 Item size : 168576 bytes