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Both the European and the American guidelines for ST-elevation myocardial infarction (STEMI) prefer ticagrelor over clopidogrel in patients after acute coronary syndromes.1,2 The landmark Platelet ...

Cardiovascular Research, Birnbaum, Yochai, Ye, Yumei

Date : 01/12/2018 Item size : 152480 bytes

The aim of this study was to investigate if IL6 trans-signalling, estimated by a ratio between the binary and ternary complexes, associates with the risk of future cardiovascular events (CVE) in a ...

Cardiovascular Research, Ziegler, Louise, Gajulapuri, Ashwini, Frumento, Paolo, Bonomi, Alice, Wallén, Håkan, de Faire, Ulf, Rose-John, Stefan, Gigante, Bruna

Date : 01/01/2019 Item size : 336192 bytes

The goal of revascularization in stable coronary artery disease (SCAD) is to relieve the myocardium from flow-limiting coronary artery disease. Positron emission tomography (PET) using tracers of ...

Cardiovascular Research, Berry, Colin, Bengel, Frank M

Date : 01/01/2019 Item size : 150596 bytes

Once released from cells by mechanical stress, inflammatory cytokines, or necrosis, extracellular IL-33 is proteolytically processed to act in an autocrine/paracrine manner as an alarmin on ...

Cardiovascular Research, Altara, Raffaele, Ghali, Rana, Mallat, Ziad, Cataliotti, Alessandro, Booz, George W, Zouein, Fouad A

Date : 01/10/2018 Item size : 912344 bytes

More than 20years ago, pivotal studies reported that an increased C-reactive protein (CRP) level predicted poor outcome in patients with acute coronary syndrome, raising the hypothesis that systemic ...

Cardiovascular Research, Ferrante, Giuseppe, Condorelli, Gianluigi

Date : 01/01/2019 Item size : 168576 bytes

Macrophages are fundamental regulators for cardiac repair after myocardial infarction (MI).1,2 While initially thought to exist in just two forms (inflammatory and anti-inflammatory), ample evidence ...

Cardiovascular Research, Lindsey, Merry L

Date : 01/10/2018 Item size : 122501 bytes

Abstract Aims In ventricular myocytes from humans and large mammals, the transverse and axial tubular system (TATS) network is less extensive than in rodents with consequently a greater proportion of ...

Cardiovascular Research, Dries, Eef, Santiago, Demetrio J, Gilbert, Guillaume, Lenaerts, Ilse, Vandenberk, Bert, Nagaraju, Chandan K, Johnson, Daniel M, Holemans, Patricia, Roderick, H Llewelyn, ...

Date : 01/09/2018 Item size : 442060 bytes

Myocardial infarction (MI) is a major threat to human health and is one of the most important diseases contributing to significant morbidity and mortality worldwide.1,2 Therapeutic strategies aimed ...

Cardiovascular Research, Meloni, Marco, Riley, Paul R, Baker, Andrew H

Date : 01/10/2018 Item size : 143806 bytes

Abstract Following a myocardial infarction (MI), the immune system helps to repair ischaemic damage and restore tissue integrity, but excessive inflammation has been implicated in adverse cardiac ...

Cardiovascular Research, Panahi, Mona, Papanikolaou, Angelos, Torabi, Azam, Zhang, Ji-Gang, Khan, Habib, Vazir, Ali, Hasham, Muneer G, Cleland, John G F, Rosenthal, Nadia A, Harding, Sian E, Sattler, ...

Date : 01/09/2018 Item size : 707987 bytes