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Methods and results Rat isolated hearts were subjected to reversible left coronary artery occlusion (ischaemia-reperfusion) and infarct size was assessed by the tetrazolium staining ...

Cardiovascular Research, Cardiac biology and remodelling, Justin S. Bice, Yvonne Keim, Johannes-Peter Stasch, Gary F. Baxter

Date : 01/02/2014 Item size : 282285 bytes

Life-threatening acute events are mainly due to rupture of unstable plaques, and the role of vascular smooth muscle cells (VSMCs) in this process in IR, Type 2 diabetes mellitus, and metabolic ...

Cardiovascular Research, Vascular biology, Sergio Martínez-Hervás, Ángela Vinué, Laura Núñez, Irene Andrés-Blasco, Laura Piqueras, José Tomás Real, Juan Francisco Ascaso, ...

Date : 15/07/2014 Item size : 352042 bytes

Abstract Objective: Most cardiac myosin binding protein C (cMyBP-C) gene mutations causing familial hypertrophic cardiomyopathy (FHC) result in C-terminal truncated proteins. By using an ...

Cardiovascular Research, Original Article, Antonio Sarikas, Lucie Carrier, Carolus Schenke, Daniela Doll, Jeanne Flavigny, Katrin S. Lindenberg, Thomas Eschenhagen, Oliver Zolk

Date : 01/04/2005 Item size : 297398 bytes

[...]platelets contribute to inflammatory processes and trigger atherosclerotic lesion progression. Conclusion GPVI-Fc preferentially bound to sites of vascular injury and was able to inhibit ...

Cardiovascular Research, Original Article, Tanja Schönberger, Dorothea Siegel-Axel, Renate Bußl, Sabine Richter, Martin S. Judenhofer, Roland Haubner, Gerald Reischl, Karin Klingel, Götz ...

Date : 01/10/2008 Item size : 249108 bytes

Methods: Chronic MI was induced in young adult (3.5 months) and aged (18 months) female SpragueDawley rats by ligation of the left coronary artery. Results: Aged control rats differed from young ...

Cardiovascular Research, Original Article, Alexander Deten, Grit Marx, Wilfried Briest, Hans Christian Volz, Heinz-Gerd Zimmer

Date : 01/05/2005 Item size : 291031 bytes

Methods and results The following parameters were evaluated: (i) number of ventricular arrhythmias in resting and stress conditions (restraint test) or after aconitine administration; (ii) cardiac ...

Cardiovascular Research, Original Article, Claudia Colussi, Roberta Berni, Jessica Rosati, Stefania Straino, Serena Vitale, Francesco Spallotta, Silvana Baruffi, Leonardo Bocchi, Francesca Delucchi, ...

Date : 01/07/2010 Item size : 280000 bytes

Abstract Objective: Our goal was to identify the ATP-sensitive potassium (KATP) channels in cardiac Purkinje cells and to document the functional properties that might distinguish them from KATP ...

Cardiovascular Research, Original Article, Peter E. Light, Jonathan M. Cordeiro, Robert J. French

Date : 01/11/1999 Item size : 327235 bytes

Methods and results In confocal fluorimetric measurements, Nrg1β1 induced a calcium-independent increase in nitric oxide (NO) production in isolated adult rat ventricular myocytes (ARVCMs) that ...

Cardiovascular Research, Original Article, Alessia Brero, Roberta Ramella, Amandine Fitou, Claudio Dati, Giuseppe Alloatti, Maria Pia Gallo, Renzo Levi

Date : 01/12/2010 Item size : 326673 bytes

An insignificant amount of MSCs was mobilized in uPAR C57BL/6J mice, whereas in wild-type animals G-CSF induced an eight-fold increase of mobilized MSCs. uPAR mice revealed up-regulated expression of ...

Cardiovascular Research, Original Article, Krishna C. Vallabhaneni, Sergey Tkachuk, Yulia Kiyan, Nelli Shushakova, Hermann Haller, Inna Dumler, Gabriele Eden

Date : 01/04/2011 Item size : 324056 bytes

Six known IL-17 family members (IL-17AF), including the prototypical IL-17A (also known as IL-17), exert potent pro-inflammatory effects and are produced by a myriad of immune cells.13 Once thought ...

Cardiovascular Research, Vascular biology, Hoanglan Nguyen, Valorie L. Chiasson, Piyali Chatterjee, Shelley E. Kopriva, Kristina J. Young, Brett M. Mitchell

Date : 15/03/2013 Item size : 350371 bytes