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Heart

In this meta-analysis of individual-patient data from 10 randomized control trials comparing beta-blockers to placebo for systolic heart failure, investigators assessed the impact of beta-blockade by ...

Heart, JournalScan, Steven M Bradley

Date : 01/01/2015
Heart

The Statin AKI Cardiac Surgery randomized control trial sought to determine if high-dose, short-term atorvastatin reduced the risk of AKI following cardiac surgery. The primary outcome of AKI was ...

Heart, JournalScan, Steven M Bradley

Date : 01/06/2016
Heart

Trial evaluated the impact of increasing testosterone concentrations on progression of atherosclerosis as determined by common carotid artery intima-media thickness and coronary artery ...

Heart, JournalScan, Steven M Bradley

Date : 01/11/2015
Heart

In this safety and efficacy study, idarucizumab was tested in a cohort of patients on dabigatran who either required an urgent surgical procedure or who had developed major bleeding. In an analysis ...

Heart, JournalScan, Steven M Bradley

Date : 15/11/2015
Heart

In this study, the authors made use of advances in DNA sequencing technology to identify mutations in protein-coding sequences (the exome) to identify genetic variants that might lower triglyceride ...

Heart, JournalScan, Steven M Bradley

Date : 01/12/2014
Heart

The Systolic Blood Pressure Intervention Trial (SPRINT) sought to determine outcomes following treatment to a target of less than 120mmHg (intensive treatment) compared with a target of less than ...

Heart, JournalScan, Steven M Bradley

Date : 15/02/2016
Heart

The Fractional Flow Reserve versus Angiography for Multivessel Evaluation (FAME) trial was a landmark study of the use of fractional flow reserve (FFR) to guide coronary revascularization through the ...

Heart, JournalScan, Steven M Bradley

Date : 15/01/2016
Heart

In the Cardiovascular Outcomes in Renal Atherosclerotic Lesions (CORAL) study, 947 patients atherosclerotic renal-artery stenosis and hypertension and/or chronic kidney disease were randomized to ...

Heart, JournalScan, Steven M Bradley

Date : 15/05/2014
Heart

A coronary artery stent that scaffolds the vessel immediately after angioplasty but disappears over time has been proposed as means to avoid complications of late stent thrombosis and restore ...

Heart, JournalScan, Steven M Bradley

Date : 01/01/2016
Heart

In this study, 150 patients with symptomatic AF who were overweight or obese were randomized to a physician led weight loss program (intervention arm) or self-directed general lifestyle measures ...

Heart, JournalScan, Steven M Bradley

Date : 01/04/2014